Background Infertility has a major impact on women’s quality of life and emotional well-being. The resulting interpersonal problems extend to women’s sexual relationships, with a high proportion of infertile women reporting sexual problems. Aim To determine the prevalence and identify the potential risk factors of female sexual dysfunction (FSD) among infertile Iranian women.\udMethods Using a cross-sectional study design including 12 infertility clinics in five Iranian cities, FSD was assessed in 604 infertile women using the culturally adapted, multidimensional Female Sexual Function Index (IV-FSFI).\udDepression, anxiety and health-related quality of life (HRQL) were also assessed for all infertile patients. Depression and anxiety were assessed with the Hospital Anxiety and Depression Scale (HADS) while HRQL was measured using the Short Form 36 (SF-36).Main outcome measure Prevalence of FSD in infertile women and associated factors.\udResults Infertile women reported significantly lower scores on the FSFI domains in comparison with healthy women. Risk factors for FSD as determined by multilevel analyses were older age and self-reported depression. Furthermore, secondary infertility, lower educational level and higher partner education put women at increased risk for FSD. Conclusions Among infertile women, sexual dysfunctions seem to be prevalent higher than previously published in Iran. This finding may have implications on the clinical assessment of sexual function and the role of demographic\udand psychological factors in infertile women.
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